4-Nitroindan → 4-Aminoindan

HRID 1042359

反応式

HRID 1042359 の反応式
[N+:1]([C:4]1[CH:12]=[CH:11][CH:10]=[C:9]2[C:5]=1[CH2:6][CH2:7][CH2:8]2)([O-])=O>CO.[Pd]>[CH2:8]1[C:9]2[C:5](=[C:4]([NH2:1])[CH:12]=[CH:11][CH:10]=2)[CH2:6][CH2:7]1

参加物

4

反応物 1

HCID 2535784-Nitroindan

生成物 1

HCID 1225694-Aminoindan

試薬・触媒・溶媒 2

HCID 23938Palladium触媒HCID 887Methanol溶媒

実験手順

4-Nitro-indan (5.00 g, 30.70 mmol) was dissolved in methanol, and Pd/C (500 mg) was added. The resulting reaction mixture was hydrogenated at 50 psi for 14 hours. Filtration through celite and concentration afforded the title indan-4-yl-amine.

後処理

  1. customThe resulting reaction mixture
  2. filtrationFiltration
  3. concentrationthrough celite and concentration

出典と根拠

ORDレコード
ord-188263aad68d460089858ec4f2183d14
出典データセット
uspto-grants-2013_10
特許番号
US08557853B2

関連ノート

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