Chloride → 2,2-Dimethyl-propionic acid 5-bromo-3-(3-chloro-benzyl)-pyrazolo[3,4-b]pyridin-1-ylmethyl ester

反応式

[Br:1][c:2]1[cH:3][c:4]2[c:5]([n:6][cH:7]1)[n:8]([CH2:12][O:13][C:14]([C:15]([CH3:16])([CH3:17])[CH3:18])=[O:19])[n:9][c:10]2[I:11].[Cl-:20].[Cl:21][c:22]1[cH:23][c:24]([CH2:25][Zn+:26])[cH:27][cH:28][cH:29]1.[O:30]1[CH2:31][CH2:32][CH2:33][CH2:34]1>>[Br:1][c:2]1[cH:3][c:4]2[c:5]([n:6][cH:7]1)[n:8]([CH2:12][O:13][C:14]([C:15]([CH3:16])([CH3:17])[CH3:18])=[O:19])[n:9][c:10]2[CH2:25][c:24]1[cH:23][c:22]([Cl:21])[cH:29][cH:28][cH:27]1