Methyl iodide → HCID 22174876、化合物
反応式
[N:1]1[CH:6]=[CH:5][CH:4]=[CH:3][C:2]=1[C:7]1[N:12]=[CH:11][N:10]=[C:9]([SH:13])[N:8]=1.[C:14](=O)([O-])[O-].[Na+].[Na+].IC>CC(C)=O>[CH3:14][S:13][C:9]1[N:8]=[C:7]([C:2]2[CH:3]=[CH:4][CH:5]=[CH:6][N:1]=2)[N:12]=[CH:11][N:10]=1参加物
5
実験手順
To a stirred suspension of the product of step 1 (0.707 g, 3.72 mmol) in acetone (36 mL) was added sodium carbonate (0.79 g, 7.5 mmol) followed by iodomethane (0.35 mL, 5.6 mmol). After overnight stirring, the reaction was filtered free of undissolved solid and concentrated to afford product as light brown solid: 1H NMR (DMSO-d6) δ 9.13 (s, 1H), 8.84-8.76 (m, 1H), 8.55-8.43 (m, 1H), 8.11-8.00 (m, 1H, 7.69-7.60 (m, 1H), 2.63 (s, 3H) ppm.
後処理
- filtrationthe reaction was filtered free of undissolved solid
- concentrationconcentrated
- customto afford product as light brown solid
出典と根拠
- ORDレコード
- ord-da937a06b3ce40bbb73ea17c83b90793
- 出典データセット
- uspto-grants-2005_11
- 特許番号
- US06969728B2
反応ノート
読み込み中…