Ammonium formate → 3-(Piperidin-4-yl)-3H-imidazo[4,5-b]pyridine
反応式
C([N:8]1[CH2:13][CH2:12][CH:11]([N:14]2[C:18]3=[N:19][CH:20]=[CH:21][CH:22]=[C:17]3[N:16]=[CH:15]2)[CH2:10][CH2:9]1)C1C=CC=CC=1.C([O-])=O.[NH4+]>[Pd].CO>[NH:8]1[CH2:9][CH2:10][CH:11]([N:14]2[C:18]3=[N:19][CH:20]=[CH:21][CH:22]=[C:17]3[N:16]=[CH:15]2)[CH2:12][CH2:13]1参加物
5
実験手順
The title compound was prepared from 130 mg of 3-(1-benzyl-piperidin-4-yl)-3-H-imidazo[4,5-b]pyridine (from Step C), 130 mg of 10% palladium on carbon and 130 mg of ammonium formate in 6 mL of MeOH, using a procedure analogous to that described in Example 95, Step C to provide 86 mg of the title compound as a solid
出典と根拠
- ORDレコード
- ord-18b7a52b906441aca7b7b0dcfa66d8af
- 出典データセット
- uspto-grants-2001_06
- 特許番号
- US06248755B1
反応ノート
読み込み中…