Ethyl bromoacetate → Ethyl [(prop-2-en-1-yl)sulfanyl]acetate

HRID 1074038ノート

反応式

HRID 1074038 の反応式
[C:1]1([CH2:7][C:8](OCC)=[S:9])C=CC=CC=1.Br[CH2:14][C:15]([O:17][CH2:18][CH3:19])=[O:16].C(S)C=C>CC[O-].[Na+]>[CH2:8]([S:9][CH2:14][C:15]([O:17][CH2:18][CH3:19])=[O:16])[CH:7]=[CH2:1]

参加物

5

反応物 3

HCID 7748Ethyl bromoacetateHCID 13367Allyl MercaptanHCID 12284387Ethyl phenylthioacetate

生成物 1

HCID 12717294Ethyl [(prop-2-en-1-yl)sulfanyl]acetate

試薬・触媒・溶媒 1

HCID 2723922Sodium ethoxide溶媒

実験手順

The procedure is as in Example 2 for the preparation of ethyl phenylthioacetate, starting with ethyl bromoacetate (16.7 g), a 2M ethanolic solution of sodium ethylate (50 cc) and allylmercaptan (7.7 cc). After purification by chromatography on a silica column with cyclohexane as eluent, ethyl (allylthio)acetate (3.1 g) is obtained, and is used in the crude state in the subsequent phases.

後処理

  1. customAfter purification by chromatography on a silica column with cyclohexane as eluent

出典と根拠

ORDレコード
ord-91f249cd31034bc2a566a3015ba0d182
出典データセット
uspto-grants-1990_11
特許番号
US04971979

反応ノート

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