Hydrochloric Acid → HCID 53684414、化合物

HRID 1075296ノート

反応式

HRID 1075296 の反応式
CCN(C1C=CC=CC=1)CC.Cl[C:13]([O:15][CH3:16])=[O:14].[CH3:17][C:18]([CH3:25])=[CH:19][CH:20]=[N:21][CH:22]([CH3:24])[CH3:23].Cl>C1(C)C=CC=CC=1.O>[CH3:16][O:15][C:13](=[O:14])[N:21]([CH:22]([CH3:24])[CH3:23])[CH:20]=[CH:19][C:18]([CH3:25])=[CH2:17]

参加物

7

反応物 4

HCID 313Hydrochloric AcidHCID 6586Methyl chloroformateHCID 7061N,N-DiethylanilineHCID 13061751HCID 13061751、化合物

生成物 1

HCID 53684414HCID 53684414、化合物

試薬・触媒・溶媒 2

HCID 962Water溶媒HCID 1140Toluene溶媒2 回

実験手順

To a stirred solution of 657 g diethylaniline in 2 l toluene is added dropwise over ca. 5 minutes 416 g methyl chloroformate. 500 g N-(3-methyl-2-butenyliden)-isopropylamine in 500 ml toluene are then added dropwise with stirring over 2 hours, maintaining the temperature between 25° and 30° C. Stirring is continued for 1 hour and the reaction mixture is then treated with 400 ml of water and 90 ml conc. hydrochloric acid. The organic phase is washed with 600 ml of saturated aqueous sodium bicarbonate solution and with 600 ml water, dried and evaporated in vacuo to give the title compound.

後処理

  1. temperaturemaintaining the temperature between 25° and 30° C
  2. stirringStirring
  3. waitis continued for 1 hour
  4. washThe organic phase is washed with 600 ml of saturated aqueous sodium bicarbonate solution and with 600 ml water
  5. customdried
  6. customevaporated in vacuo

出典と根拠

ORDレコード
ord-aa1d08e4817846348427496304dc5457
出典データセット
uspto-grants-1983_07
特許番号
US04395550

反応ノート

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