Xanthene → Xanthone

HRID 1076900

反応式

HRID 1076900 の反応式
[Cr](O[Cr]([O-])(=O)=O)([O-])(=O)=O.[Cr](O[Cr]([O-])(=O)=O)([O-])(=O)=O.[Na+].[Na+].[Cr](O[Cr]([O-])(=O)=O)([O-])(=O)=[O:22].[K+].[K+].[CH:32]1[C:45]2[CH2:44][C:43]3[C:38](=[CH:39][CH:40]=[CH:41][CH:42]=3)[O:37][C:36]=2[CH:35]=[CH:34][CH:33]=1>C(O)(=O)C.C(O)(C)(C)C.O>[CH:32]1[C:45]2[C:44](=[O:22])[C:43]3[C:38](=[CH:39][CH:40]=[CH:41][CH:42]=3)[O:37][C:36]=2[CH:35]=[CH:34][CH:33]=1

参加物

8

反応物 4

HCID 7107Xanthene2 回HCID 24502Potassium DichromateHCID 24503Dichromate ionHCID 25408Sodium Dichromate2 回

生成物 1

HCID 7020Xanthone

試薬・触媒・溶媒 3

HCID 176Acetic Acid溶媒2 回HCID 962Water溶媒HCID 6386tert-Butanol溶媒

実験手順

The above oxidation reaction may be carried out using dichromate anion such as sodium dichromate or potassium dichromate as the oxidizing agent. The reaction will proceed in from 15 minutes to 6 hours at a temperature of from 80° to 120°C. The amount of oxidizing agent is limited to the stoichiometric quantity required for oxidation of the 9-methylene group of the xanthene derivative. Suitable solvents for this conversion are, for example, water, acetic acid, tert-butyl alcohol, and the like, or combinations of these solvents. For example, by combining three moles of the xanthene derivative, Formula II, dissolved in acetic acid with four moles of sodium dichromate and refluxing the mixture for 1 to 3 hours, the corresponding xanthen-9-one derivative, Formula III, can be obtained.

後処理

  1. customThe above oxidation reaction
  2. customThe reaction
  3. customwill proceed in from 15 minutes to 6 hours at a temperature of from 80° to 120°C
  4. temperaturerefluxing the mixture for 1 to 3 hours

出典と根拠

ORDレコード
ord-c3c3123c34a842918312ec9639ac1e9c
出典データセット
uspto-grants-1976_05
特許番号
US03957989

関連ノート

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