Chloride → HCID 20062412、化合物

HRID 1084799ノート

反応式

HRID 1084799 の反応式
[CH:1](=[N:6][OH:7])[C:2]([CH3:5])([CH3:4])[CH3:3].ClN1C(=O)CCC1=O.[Cl-].[CH:17]([P:19]([CH3:23])(=[O:22])[O:20][CH3:21])=[CH2:18].C(N(CC)CC)C>ClCCl.N1C=CC=CC=1>[C:2]([C:1]1[CH2:18][CH:17]([P:19]([CH3:23])(=[O:22])[O:20][CH3:21])[O:7][N:6]=1)([CH3:5])([CH3:4])[CH3:3]

参加物

8

反応物 5

HCID 312ChlorideHCID 8471TriethylamineHCID 31398ChlorosuccinimideHCID 136457PivalaldoximeHCID 6454580Methyl methylvinylphosphinate

生成物 1

HCID 20062412HCID 20062412、化合物収率 50%

試薬・触媒・溶媒 2

HCID 1049Pyridine溶媒HCID 6344Dichloromethane溶媒

実験手順

40.4 g (0.4 mol) of pivalaldoxime are converted in analogy to Example 1(a) with 58.7 g (0.44 mol) of N-chlorosuccinimide and 2 ml of pyridine in dichloromethane into the hydroxamoyl chloride which is subsequently reacted with 52.8 g (0.44 mol) of methyl vinyl(P-methyl)phosphinate and 61.2 ml (0.44 mol) of triethylamine, and worked up, as described in Example 1(b), the oily product being obtained with a yield of about 50%.

後処理

  1. customthe oily product being obtained with a yield of about 50%

出典と根拠

ORDレコード
ord-a497d412dcde41f0bf2239586dc15ebe
出典データセット
uspto-grants-1991_04
特許番号
US05006515

反応ノート

読み込み中…