1-Chloro-4-(chloromethyl)benzene → HCID 19938671、化合物
反応式
[H-].[Na+].[CH3:3][CH:4]1[CH2:8][CH2:7][CH:6]([C:9](OC)=O)[C:5]1=[O:13].[Cl:14][C:15]1[CH:22]=[CH:21][C:18](CCl)=[CH:17][CH:16]=1>C1C=CC=CC=1>[Cl:14][C:15]1[CH:22]=[CH:21][C:18]([CH2:9][CH:6]2[CH2:7][CH2:8][CH:4]([CH3:3])[C:5]2=[O:13])=[CH:17][CH:16]=1参加物
5
実験手順
Into 126 ml of anhydrous benzene, 3.04 g of sodium hydride (prepared by washing 60 % oily sodium hydride with anhydrous benzene) were added, and then 18 g of methyl 3-methyl-2-oxocyclopentanecarboxylate were added to the thus formed mixture. After stirring the whole mixture for one hour at room temperature, 21.5 g of 4-chlorobenzyl chloride were added to the mixture and the thus obtained mixture was refluxed for 6 hours in an oil bath at 90° C.
後処理
- temperaturethe thus obtained mixture was refluxed for 6 hours in an oil bath at 90° C.
出典と根拠
- ORDレコード
- ord-96ad24c2bb574b9a924a79a736093807
- 出典データセット
- uspto-grants-1991_07
- 特許番号
- US05028254
反応ノート
読み込み中…