m-Chloroperbenzoic acid → 4-(4-(2-Quinolinylmethylsulfinyl)styryl)benzoic acid

HRID 1086235

反応式

HRID 1086235 の反応式
[N:1]1[C:10]2[C:5](=[CH:6][CH:7]=[CH:8][CH:9]=2)[CH:4]=[CH:3][C:2]=1[CH2:11][S:12][C:13]1[CH:29]=[CH:28][C:16]([CH:17]=[CH:18][C:19]2[CH:27]=[CH:26][C:22]([C:23]([OH:25])=[O:24])=[CH:21][CH:20]=2)=[CH:15][CH:14]=1.ClC1C=CC=C(C(OO)=[O:38])C=1.C(=O)([O-])O.[K+]>ClC=CCl>[N:1]1[C:10]2[C:5](=[CH:6][CH:7]=[CH:8][CH:9]=2)[CH:4]=[CH:3][C:2]=1[CH2:11][S:12]([C:13]1[CH:29]=[CH:28][C:16]([CH:17]=[CH:18][C:19]2[CH:20]=[CH:21][C:22]([C:23]([OH:25])=[O:24])=[CH:26][CH:27]=2)=[CH:15][CH:14]=1)=[O:38]

参加物

5

反応物 3

HCID 70297m-Chloroperbenzoic acidHCID 516893Potassium BicarbonateHCID 541560444-(4-(2-Quinolinylmethylthio)styryl)benzoic acid

生成物 1

HCID 545127564-(4-(2-Quinolinylmethylsulfinyl)styryl)benzoic acid

試薬・触媒・溶媒 1

HCID 109001,2-Dichloroethylene溶媒

実験手順

4-(4-(2-quinolinylmethylthio)styryl)benzoic acid (4 mmol) in dichloroethene (50 ml) is stirred with m-chloroperbenzoic acid (4 mmol) and solid potassium hydrogen carbonate (1.0 g). The reaction is assayed by TLC and upon consumption of the starting thio compound, the mixture is filtered, washed with dilute aqueous sodium bisulfite, dried and evaporated to give 4-(4-(2-quinolinylmethylsulfinyl)-styryl)benzoic acid.

後処理

  1. customThe reaction is assayed by TLC and upon consumption of the starting thio compound
  2. filtrationthe mixture is filtered
  3. washwashed with dilute aqueous sodium bisulfite
  4. customdried
  5. customevaporated

出典と根拠

ORDレコード
ord-ff1d838880254f66a04a42c3a38b6c5d
出典データセット
uspto-grants-1991_07
特許番号
US05028615

関連ノート

読み込み中…