1-Propanol → Propyl pyrazinoate

HRID 1088238ノート

反応式

HRID 1088238 の反応式
[N:1]1[CH:6]=[CH:5][N:4]=[CH:3][C:2]=1[C:7](Cl)=[O:8].N1C=C[CH:13]=[CH:12][CH:11]=1.C([OH:19])CC>C(Cl)Cl>[N:1]1[CH:6]=[CH:5][N:4]=[CH:3][C:2]=1[C:7]([O:8][CH2:11][CH2:12][CH3:13])=[O:19]

参加物

5

反応物 3

HCID 10311-PropanolHCID 1049PyridineHCID 88279Pyrazinecarbonyl chloride

生成物 1

HCID 72507Propyl pyrazinoate

試薬・触媒・溶媒 1

HCID 6344Dichloromethane溶媒

実験手順

To 4.0 g (28 mmol) of pyrazinoyl chloride dissolved in methylene chloride (20 mL) and pyridine (2 mL) cooled to 0° C. in a 50 mL round bottom flask was added n-propyl alcohol (4.0 g, 66 mmol). Completion of the reaction and separation as described above, followed by distillation, led to isolation of the title compound as a water white oil; b.p: 68°-73° C. at 0.20 mm Hg.

後処理

  1. customCompletion of the reaction and separation
  2. distillationfollowed by distillation

出典と根拠

ORDレコード
ord-5e35d677b44e4426bd94407fb40b664c
出典データセット
uspto-grants-1990_10
特許番号
US04962111

反応ノート

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