Ethyl p-methylbenzenesulfonate → 2,4-Dimethyl-3-ethyl-5-ethoxycarbonyl-thiazolium p-toluene-sulfonate
反応式
Cl[CH:2]([C:8]([CH3:10])=O)[C:3]([O:5][CH2:6][CH3:7])=[O:4].C(N)(=S)C.[CH3:15][C:16]1[S:17][CH:18](C(OCC)=O)[CH:19](C)[N:20]=1.[C:27]1([CH3:39])[CH:32]=[CH:31][C:30]([S:33]([O:36]CC)(=[O:35])=[O:34])=[CH:29][CH:28]=1>>[C:27]1([CH3:39])[CH:28]=[CH:29][C:30]([S:33]([O-:36])(=[O:34])=[O:35])=[CH:31][CH:32]=1.[CH3:15][C:16]1[S:17][C:2]([C:3]([O:5][CH2:6][CH3:7])=[O:4])=[C:8]([CH3:10])[N+:20]=1[CH2:19][CH3:18]参加物
5
実験手順
Ethyl 2-chloro-acetoacetate is condensed with thioacetamide to 2,4-dimethyl-5-ethoxycarbonyl-thiazoline which is reacted, analogously to Preparation Example 1 A, with ethyl p-toluenesulfonate to give the p-toluenesulfonate of the quaternary ammonium base.