3-Pyridinemethanol → 2-(Pyridin-3-yloxy)acetonitrile
反応式
N1C=CC=C(C[O:8][CH2:9][CH2:10][NH2:11])C=1.[Na].[N:13]1[CH:18]=[CH:17][CH:16]=[C:15](CO)[CH:14]=1.ClCC#N>CN(C)C=O>[N:13]1[CH:18]=[CH:17][CH:16]=[C:15]([O:8][CH2:9][C:10]#[N:11])[CH:14]=1参加物
6
実験手順
The starting amine, (3-pyridinyl)methyloxyethylamine, was prepared by the following procedure: reaction of the sodium salt of 3-pyridinylmethanol and chloracetonitrile in dimethylformamide gave 2-(3-pyridinyloxy)acetonitrile, which, upon reduction with borane in tetrahydroduran solution, gave the desired amine.
出典と根拠
- ORDレコード
- ord-f651c32dc42d41d5956b9b9d5d8f681f
- 出典データセット
- uspto-grants-1992_01
- 特許番号
- US05081131
反応ノート
読み込み中…