反応式
Cl[C:2]1[CH2:7][CH2:6][CH2:5][CH2:4][C:3]=1[C:8]#[N:9].[Se-2:10].[Na+].[Na+].Cl[CH2:14][C:15]#[N:16].[OH-].[Na+]>>[NH2:9][C:8]1[C:3]2[CH2:4][CH2:5][CH2:6][CH2:7][C:2]=2[Se:10][C:14]=1[C:15]#[N:16]参加物
5
実験手順
The 3-amino-4,5,6,7-tetrahydrobenzo[1,2-b]selenophene-2-carbonitrile is prepared starting from 2-chlorocyclohex-1-enecarbonitrile, sodium selenide and chloroacetonitrile, which on treatment with aqueous sodium hydroxide gave the corresponding amide in good yield. Diazotization of the amine with sodium nitrite followed by treatment with iodomethane in presence of a base gave the required 3-methyl-6,7,8,9-tetrahydrobenzo[1,2-b]1,2,3-triazino-[4,5-d]-selenophen-4-one (compound 14).
出典と根拠
- ORDレコード
- ord-c00d8f15095a451b8ea9a4115a04e0ff
- 出典データセット
- uspto-grants-2012_03
- 特許番号
- US08143237B2
関連ノート
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