Tetrahydrofuran → (S)-3-{[(benzyloxy)carbonyl][3-(trifluoromethyl)benzyl]amino}-4-oxo-4,6,7,8-tetrahydropyrrolo[1,2-a]pyrimidine-6-carboxylic Acid

反応式

[CH2:1]([O:8][C:9](=[O:41])[NH:10][C:11]1[C:16](=[O:17])[N:15]2[CH:18]([C:21](=[O:40])NCC3C=CC(C(NC(OC(C)(C)C)=O)=N)=CC=3)[CH2:19][CH2:20][C:14]2=[N:13][CH:12]=1)[C:2]1[CH:7]=[CH:6][CH:5]=[CH:4][CH:3]=1.[F:42][C:43]([F:53])([F:52])[C:44]1[CH:45]=[C:46]([CH:49]=[CH:50][CH:51]=1)[CH2:47]Br.[H-].[Na+].C1C[O:59]CC1>CCCC[N+](CCCC)(CCCC)CCCC.[I-]>[CH2:1]([O:8][C:9]([N:10]([CH2:47][C:46]1[CH:49]=[CH:50][CH:51]=[C:44]([C:43]([F:53])([F:52])[F:42])[CH:45]=1)[C:11]1[C:16](=[O:17])[N:15]2[C@H:18]([C:21]([OH:59])=[O:40])[CH2:19][CH2:20][C:14]2=[N:13][CH:12]=1)=[O:41])[C:2]1[CH:7]=[CH:6][CH:5]=[CH:4][CH:3]=1