Methyl iodide → 3-Methylmercapto-4-n-butyl-1,2,4-triazole
反応式
I[CH3:2].[SH:3][C:4]1[N:8]([CH2:9][CH2:10][CH2:11][CH3:12])[CH:7]=[N:6][N:5]=1.[OH-].[Na+]>CO>[CH3:2][S:3][C:4]1[N:8]([CH2:9][CH2:10][CH2:11][CH3:12])[CH:7]=[N:6][N:5]=1参加物
5
実験手順
Iodomethane (9.05 g. or 0.0637 mole) was added to a solution of 10 g. of 3-mercapto-4-n-butyl-1,2,4-triazole, methanol (100 ml.), and sodium hydroxide (2.55 g. or 0.0637 mole). This solution was then refluxed for 2 hours. The solvent was then removed in vacuum and the residue was dissolved in benzene. This solution was washed with water, dried and the benzene removed in vacuum. The residual oil was distilled to give 3-methylmercapto-4-n-butyl-1,2,4-triazole, b.p. 128°-131° C./ 2 mm. The structure was confirmed by its nuclear magnetic resonance spectrum.
後処理
- temperatureThis solution was then refluxed for 2 hours
- customThe solvent was then removed in vacuum
- dissolutionthe residue was dissolved in benzene
- washThis solution was washed with water
- customdried
- customthe benzene removed in vacuum
- distillationThe residual oil was distilled
出典と根拠
- ORDレコード
- ord-5e282fa862044fe388add7e410aefa20
- 出典データセット
- uspto-grants-1978_10
- 特許番号
- US04120864
反応ノート
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