Tetrahydrofuran → Methyl 5-{[4-methyl-5-(5-{[(2-morpholin-4-ylethyl)amino]sulfonyl}-2-thienyl)-1,3-thiazol-2-yl]amino}-5-oxopentanoate

反応式

[B-:25]([F:26])([F:27])([F:28])[F:29].[C:47]([CH2:48][CH2:49][CH2:50][C:51](=[O:52])[O-:53])(=[O:54])[O:55][CH3:56].[CH2:66]1[O:67][CH2:68][CH2:69][CH2:70]1.[CH:57]([N:58]([CH2:59][CH3:60])[CH:61]([CH3:62])[CH3:63])([CH3:64])[CH3:65].[NH2:1][c:2]1[s:3][c:4](-[c:8]2[cH:9][cH:10][c:11]([S:13](=[O:14])(=[O:15])[NH:16][CH2:17][CH2:18][N:19]3[CH2:20][CH2:21][O:22][CH2:23][CH2:24]3)[s:12]2)[c:5]([CH3:7])[n:6]1.[n:30]1([O:31][C:32]([N:33]([CH3:34])[CH3:35])=[N+:36]([CH3:37])[CH3:38])[c:39]2[cH:40][cH:41][cH:42][cH:43][c:44]2[n:45][n:46]1>>[NH:1]([c:2]1[s:3][c:4](-[c:8]2[cH:9][cH:10][c:11]([S:13](=[O:14])(=[O:15])[NH:16][CH2:17][CH2:18][N:19]3[CH2:20][CH2:21][O:22][CH2:23][CH2:24]3)[s:12]2)[c:5]([CH3:7])[n:6]1)[C:51]([CH2:50][CH2:49][CH2:48][C:47](=[O:54])[O:55][CH3:56])=[O:52]