Ammonium → Tert-butyl 3-(3-chloro-2-fluorophenyl)-3-hydroxypyrrolidine-1-carboxylate

HRID 1118133

反応式

[Br:1][c:2]1[c:3]([F:9])[c:4]([Cl:8])[cH:5][cH:6][cH:7]1.[C:15](=[O:16])([O:17][C:18]([CH3:19])([CH3:20])[CH3:21])[N:22]1[CH2:23][C:24](=[O:27])[CH2:25][CH2:26]1.[CH2:10]([Li:11])[CH2:12][CH2:13][CH3:14].[Cl-:28].[NH4+:29].[O:30]1[CH2:31][CH2:32][CH2:33][CH2:34]1>>[c:2]1([C:24]2([OH:27])[CH2:23][N:22]([C:15](=[O:16])[O:17][C:18]([CH3:19])([CH3:20])[CH3:21])[CH2:26][CH2:25]2)[c:3]([F:9])[c:4]([Cl:8])[cH:5][cH:6][cH:7]1