1-Iodopropane → methyl N-propyl-4-iodo-2-pyrrolecarboxylate

反応式

[I:1][C:2]1[CH:3]=[C:4]([C:7]([O:9][CH3:10])=[O:8])[NH:5][CH:6]=1.I[CH2:12][CH2:13][CH3:14]>>[CH2:12]([N:5]1[CH:6]=[C:2]([I:1])[CH:3]=[C:4]1[C:7]([O:9][CH3:10])=[O:8])[CH2:13][CH3:14]

参加物

反応物 2

HCID 336431-Iodopropane

HCID 11673249methyl 4-iodo-1H-pyrrole-2-carboxylate

生成物 1

HCID 19694682methyl N-propyl-4-iodo-2-pyrrolecarboxylate収率 64.7%

実験手順

Following the basic procedure of Example 7(d), by reacting 1.96 g (7.8 mmol) of methyl 4-iodo-2-pyrrolecarboxylate with 940 μl (9.6 mmol) of 3-iodopropane, 1.48 g (64%) of methyl N-propyl-4-iodo-2-pyrrolecarboxylate was obtained in the form of a slightly yellow oil.

出典と根拠

ORDレコード: ord-5fa351dbe3ea452bbf01e7f31dec9368
出典データセット: uspto-grants-1998_03
DOI: 10.6084/m9.figshare.5104873.v1
特許番号: US05723499

反応ノート

読み込み中…