Chloride → 3-bromo-8-fluoro-12-(4-methylpiperazin-1-yl)-6H-[1]benzothieno[2,3-b][1,5]benzodiazepine

反応式

[Br:1][c:2]1[cH:3][cH:4][c:5]2[c:6]([s:7][c:8]([NH:15][c:16]3[c:17]([NH2:23])[cH:18][cH:19][c:20]([F:22])[cH:21]3)[c:9]2[C:10]([O:11][CH2:12][CH3:13])=[O:14])[cH:24]1.[CH3:25][N:26]1[CH2:27][CH2:28][NH:29][CH2:30][CH2:31]1.[CH3:32][O:33][c:34]1[cH:35][cH:36][cH:37][cH:38][cH:39]1.[Cl-:40].[Cl-:41].[Cl-:42].[Cl-:43].[Ti+4:44]>>[Br:1][c:2]1[cH:3][cH:4][c:5]2[c:6]([s:7][c:8]3[c:9]2[C:10]([N:29]2[CH2:28][CH2:27][N:26]([CH3:25])[CH2:31][CH2:30]2)=[N:23][c:17]2[c:16]([cH:21][c:20]([F:22])[cH:19][cH:18]2)[NH:15]3)[cH:24]1