Chloride → 2-(3-Bromo-phenyl)-2-tert-butoxycarbonylamino-3,3,3-trifluoro-propionic acid ethyl ester

反応式

[Br:1][c:2]1[cH:3][c:4]([I:8])[cH:5][cH:6][cH:7]1.[CH2:14]([CH3:15])[O:16][C:17]([C:18]([C:19]([F:20])([F:21])[F:22])=[N:23][C:24](=[O:25])[O:26][C:27]([CH3:28])([CH3:29])[CH3:30])=[O:31].[CH2:32]1[O:33][CH2:34][CH2:35][CH2:36]1.[CH:10]([Mg+:11])([CH3:12])[CH3:13].[Cl-:9]>>[Br:1][c:2]1[cH:3][c:4]([C:18]([C:17]([O:16][CH2:14][CH3:15])=[O:31])([C:19]([F:20])([F:21])[F:22])[NH:23][C:24](=[O:25])[O:26][C:27]([CH3:28])([CH3:29])[CH3:30])[cH:5][cH:6][cH:7]1