Tetrahydrofuran → N-(2,6-difluorophenyl)-3-[3-(2-{[2-methyl-4-({1-[2-(methylsulfonyl)ethyl]-4-piperidinyl}oxy)phenyl]amino}-4-pyrimidinyl)imidazo[1,2-a]pyridin-2-yl]benzamide

反応式

[CH2:54]1[O:55][CH2:56][CH2:57][CH2:58]1.[CH:48](=[CH2:49])[S:50](=[O:51])(=[O:52])[CH3:53].[F:1][c:2]1[c:3]([NH:9][C:10]([c:11]2[cH:12][c:13](-[c:17]3[n:18][c:19]4[n:20]([cH:21][cH:22][cH:23][cH:24]4)[c:25]3-[c:26]3[n:27][c:28]([NH:32][c:33]4[c:34]([CH3:46])[cH:35][c:36]([O:39][CH:40]5[CH2:41][CH2:42][NH:43][CH2:44][CH2:45]5)[cH:37][cH:38]4)[n:29][cH:30][cH:31]3)[cH:14][cH:15][cH:16]2)=[O:47])[c:4]([F:8])[cH:5][cH:6][cH:7]1>>[F:1][c:2]1[c:3]([NH:9][C:10]([c:11]2[cH:12][c:13](-[c:17]3[n:18][c:19]4[n:20]([cH:21][cH:22][cH:23][cH:24]4)[c:25]3-[c:26]3[n:27][c:28]([NH:32][c:33]4[c:34]([CH3:46])[cH:35][c:36]([O:39][CH:40]5[CH2:41][CH2:42][N:43]([CH2:49][CH2:48][S:50](=[O:51])(=[O:52])[CH3:53])[CH2:44][CH2:45]5)[cH:37][cH:38]4)[n:29][cH:30][cH:31]3)[cH:14][cH:15][cH:16]2)=[O:47])[c:4]([F:8])[cH:5][cH:6][cH:7]1