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Eugenol → 2-Methoxy-4-[3-(triethoxysilyl)propyl]phenol

HRID 1158560
ノート
印刷プレビュー

反応式

HRID 1158560 の反応式
[CH3:1][O:2][C:3]1[CH:4]=[C:5]([CH2:10][CH:11]=[CH2:12])[CH:6]=[CH:7][C:8]=1[OH:9].[CH2:13]([O:15][SiH:16]([O:20][CH2:21][CH3:22])[O:17][CH2:18][CH3:19])[CH3:14]>[Pt].[H+].[H+].Cl[Pt-2](Cl)(Cl)(Cl)(Cl)Cl.C(O)(C)C>[CH3:1][O:2][C:3]1[CH:4]=[C:5]([CH2:10][CH2:11][CH2:12][Si:16]([O:20][CH2:21][CH3:22])([O:17][CH2:18][CH3:19])[O:15][CH2:13][CH3:14])[CH:6]=[CH:7][C:8]=1[OH:9]
参加物反応条件実験手順後処理出典と根拠反応ノート

参加物

6

反応物 2

HCID 3314EugenolHCID 13830Triethoxysilane

生成物 1

HCID 231177322-Methoxy-4-[3-(triethoxysilyl)propyl]phenol収率 88%

試薬・触媒・溶媒 3

HCID 23939Platinum触媒HCID 61859Chloroplatinic acid触媒HCID 3776Isopropanol溶媒

反応条件

温度
55 °C

実験手順

Into a four-neck flask provided with a stirrer, a reflux condenser, a dropping funnel and a thermometer were added 164 g (1.0 mole) of 3-(3-methoxy-4-hydroxyphenyl)propene and 100 ppm in terms of platinum metal of a 2 mass % isopropanol solution of chloroplatinic acid. Then 164 g (1.0 mole) of triethoxysilane was dripped over the course of five hours from a dropping funnel and was reacted while the mixture was heated and stirred at a temperature in the range from 50 to 60° C. After the reaction was completed, vacuum distillation was performed and 289 g (0.88 mole) of the desired product (3-(3-methoxy-4-hydroxyphenyl)propyl triethoxysilane) were obtained. The yield was 88%.

後処理

  1. customInto a four-neck flask provided with a stirrer, a reflux condenser, a dropping funnel
  2. customwas reacted while the mixture
  3. temperaturewas heated
  4. distillationvacuum distillation

出典と根拠

ORDレコード
ord-9f499f745cc8436ea450a875e9a5fbae
出典データセット
uspto-grants-2010_10
DOI
10.6084/m9.figshare.5104873.v1
特許番号
US07811637B2

反応ノート

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