(+-)-4-Hydroxymandelic acid → Sodium 4-hydroxyphenylglycolate
反応式
[OH:1][C:2]1[CH:12]=[CH:11][C:5]([CH:6]([OH:10])[C:7]([OH:9])=[O:8])=[CH:4][CH:3]=1.[OH-].[Na+:14]>C(C(C)=O)C(C)C>[OH:1][C:2]1[CH:12]=[CH:11][C:5]([CH:6]([OH:10])[C:7]([O-:9])=[O:8])=[CH:4][CH:3]=1.[Na+:14]参加物
4
反応条件
- 温度
- 20 °C
実験手順
The procedure of Example 1 was repeated except that the organic phase containing p-hydroxymandelic acid was treated with a molar equivalent of sodium hydroxide as a 50% w/w aqueous solution. The caustic solution was added over one hour during which time the methyl isobutyl ketone solution was maintained at about 20° C. with cooling. The precipitate of sodium p-hydroxymandelate monohydrate was filtered off and suctioned as dry as possible before drying under vacuum at 40° C.
後処理
- temperaturewith cooling
- filtrationThe precipitate of sodium p-hydroxymandelate monohydrate was filtered off
- customas dry as possible
- custombefore drying under vacuum at 40° C.
出典と根拠
- ORDレコード
- ord-efc510c327f446478b2c1dfe275dffcd
- 出典データセット
- uspto-grants-1983_01
- 特許番号
- US04368334
反応ノート
読み込み中…