Potassium Carbonate → N-(1-{4'-[3-Methyl-4-(6-phenyl-pyridin-2-ylamino)-isoxazol-5-yl]-biphenyl-4-yl}-cyclopropanecarbonyl)-methanesulfonamide

反応式

[NH2:1][C:2]1[C:3]([CH3:29])=[N:4][O:5][C:6]=1[C:7]1[CH:12]=[CH:11][C:10]([C:13]2[CH:18]=[CH:17][C:16]([C:19]3([C:22]([NH:24][S:25]([CH3:28])(=[O:27])=[O:26])=[O:23])[CH2:21][CH2:20]3)=[CH:15][CH:14]=2)=[CH:9][CH:8]=1.Br[C:31]1[CH:36]=[CH:35][CH:34]=[C:33]([C:37]2[CH:42]=[CH:41][CH:40]=[CH:39][CH:38]=2)[N:32]=1.C(=O)([O-])[O-].[K+].[K+].C1C=CC(P(C2C(C3C(P(C4C=CC=CC=4)C4C=CC=CC=4)=CC=C4C=3C=CC=C4)=C3C(C=CC=C3)=CC=2)C2C=CC=CC=2)=CC=1>C1COCC1.C([O-])(=O)C.[Pd+2].C([O-])(=O)C>[CH3:29][C:3]1[C:2]([NH:1][C:31]2[CH:36]=[CH:35][CH:34]=[C:33]([C:37]3[CH:38]=[CH:39][CH:40]=[CH:41][CH:42]=3)[N:32]=2)=[C:6]([C:7]2[CH:8]=[CH:9][C:10]([C:13]3[CH:14]=[CH:15][C:16]([C:19]4([C:22]([NH:24][S:25]([CH3:28])(=[O:27])=[O:26])=[O:23])[CH2:21][CH2:20]4)=[CH:17][CH:18]=3)=[CH:11][CH:12]=2)[O:5][N:4]=1