Methyl iodide → 1,4-Dimethylpyridinium Iodide

HRID 1188760ノート

反応式

HRID 1188760 の反応式
[N:1]1[CH:6]=[CH:5][C:4]([CH3:7])=[CH:3][CH:2]=1.[CH3:8][I:9]>C1(C)C=CC=CC=1>[I-:9].[CH3:8][N+:1]1[CH:6]=[CH:5][C:4]([CH3:7])=[CH:3][CH:2]=1

参加物

4

反応物 2

HCID 6328Methyl iodideHCID 79634-Methylpyridine

生成物 1

HCID 2006031,4-Dimethylpyridinium Iodide収率 67.2%

試薬・触媒・溶媒 1

HCID 1140Toluene溶媒

実験手順

To a solution of 4-picoline (18.6 g, 0.2 mol) in toluene (100 mL), methyl iodide (56.8 g, 0.4 mol) was added dropwise at room temperature. After the addition, the mixture was stirred at room temperature for 5 hrs. The precipitate was collected by filtration, washed with toluene and dried under vacuum to give Compound 7 as an off-white solid (31.6 g, 67%). The structure of Compound 7 is given below:

後処理

  1. additionAfter the addition
  2. filtrationThe precipitate was collected by filtration
  3. washwashed with toluene
  4. customdried under vacuum

出典と根拠

ORDレコード
ord-5fbfbab387164d6fb131ad5a8c7cbe9e
出典データセット
uspto-grants-2014_03
特許番号
US08674102B2

反応ノート

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