Chloroform → HCID 22411936、化合物
反応式
[C:1]1([C:7]2[NH:8][C:9]([CH3:17])=[C:10]([CH:12](O)[CH:13]([CH3:15])[CH3:14])[N:11]=2)[CH:6]=[CH:5][CH:4]=[CH:3][CH:2]=1.C(Cl)(Cl)[Cl:19]>S(Cl)(Cl)=O>[ClH:19].[C:1]1([C:7]2[NH:8][C:9]([CH3:17])=[C:10]([CH:12]([Cl:19])[CH:13]([CH3:15])[CH3:14])[N:11]=2)[CH:6]=[CH:5][CH:4]=[CH:3][CH:2]=1参加物
4
実験手順
27 g of 2-phenyl-4-(1-hydroxy-2-methylpropyl)-5-methyl-1H-imidazole are dissolved in 700 ml of chloroform with 44 ml of thionyl chloride (SOCl2) and refluxed for 5 hours. 2-Phenyl-5-methyl-4-(1-chloro-2-methylpropyl)-1H-imidazole hydrochloride is isolated in quantitative yield.
後処理
- temperaturerefluxed for 5 hours
出典と根拠
- ORDレコード
- ord-0c7e1c73f80e439a9c1d3a4e58a8e903
- 出典データセット
- uspto-grants-1994_01
- 特許番号
- US05276034
反応ノート
読み込み中…