Octanal → HCID 11063309、化合物

HRID 1198632ノート

反応式

[CH:1](=O)[CH2:2][CH2:3][CH2:4][CH2:5][CH2:6][CH2:7][CH3:8].[C:10]1(=[O:15])[CH2:14][CH2:13][CH2:12][CH2:11]1.[OH-].[Na+]>>[CH:1](=[C:11]1/[C:10](=[O:15])[CH2:14][CH2:13][CH2:12]/1)\[CH2:2][CH2:3][CH2:4][CH2:5][CH2:6][CH2:7][CH3:8]

参加物

反応物 3

HCID 454Octanal

HCID 8452Cyclopentanone

HCID 14798Sodium Hydroxide

生成物 1

HCID 11063309HCID 11063309、化合物

実験手順

The procedure was similar to that in Example 1 by reacting n-octanal with cyclopentanone in the presence of 1% NaOH to give 2-(E)-octylidene cyclopentanone. The boiling point of this intermediate compound was determined to be 120°-125° C. at a pressure of 4 mm Hg. A subsequent Mannich reaction yielded the 2-Dimethylaminomethyl-5-(E)-octylidene cyclopentanone hydrochloride. The melting point of the product was determined to be 138°-140° C.

出典と根拠

ORDレコード: ord-e334e9397c014eccad1d53635a6616ce
出典データセット: uspto-grants-1994_01
DOI: 10.6084/m9.figshare.5104873.v1
特許番号: US05281622

反応ノート

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