Hydroxyamine hydrochloride → HCID 136364583、化合物

HRID 1200033ノート

反応式

HRID 1200033 の反応式
[Na].[C:2]([C:5]1[CH:6]=[CH:7][C:8]([C:11]#[N:12])=[N:9][CH:10]=1)([OH:4])=[O:3].Cl.[NH2:14][OH:15]>C(O)C>[C:2]([C:5]1[CH:6]=[CH:7][C:8]([C:11](=[N:14][OH:15])[NH2:12])=[N:9][CH:10]=1)([OH:4])=[O:3]

参加物

5

反応物 3

HCID 443297Hydroxyamine hydrochlorideHCID 27611086-Cyanopyridine-3-carboxylic acidHCID 5360545Sodium2 回

生成物 1

HCID 136364583HCID 136364583、化合物

試薬・触媒・溶媒 1

HCID 702Ethanol溶媒

実験手順

Sodium (18 mmol) is added to a flask containing 20 ml of ethanol. After the sodium has dissolved, 3.8 mmol of 5-carboxy-2-cyanopyridine and 18 mmol of hydroxylamine hydrochloride are added, and the solution is refluxed for 5 h. After cooling, the resulting precipitate is filtered off and recrystallized from water; m.p.>300°.

後処理

  1. temperaturethe solution is refluxed for 5 h
  2. temperatureAfter cooling
  3. filtrationthe resulting precipitate is filtered off
  4. customrecrystallized from water

出典と根拠

ORDレコード
ord-431e14a2a21948e6bbabb6164684945e
出典データセット
uspto-grants-1990_02
特許番号
US04904675

反応ノート

読み込み中…