2-Cyclohexen-1-one, 4,4-dimethyl- → Cyclohexanone, 4,4-dimethyl-

HRID 12023

反応式

HRID 12023 の反応式
[CH3:1][C:2]1([CH3:9])[CH2:7][CH2:6][C:5](=[O:8])[CH:4]=[CH:3]1.[H][H]>C(OCC)(=O)C.[Pd]>[CH3:1][C:2]1([CH3:9])[CH2:7][CH2:6][C:5](=[O:8])[CH2:4][CH2:3]1

参加物

5

反応物 2

HCID 1368392-Cyclohexen-1-one, 4,4-dimethyl-HCID 178418361HCID 178418361、化合物

生成物 1

HCID 138166Cyclohexanone, 4,4-dimethyl-収率 94%

試薬・触媒・溶媒 2

HCID 23938Palladium触媒HCID 8857Ethyl Acetate溶媒

実験手順

A solution of 4,4-dimethyl-cyclohex-2-enone (3 mmol) in ethyl acetate is hydrogenated overnight at room temperature using Pd/C (0.05 mmol) with hydrogen under normal pressure. Filtration over celite and then concentration by evaporation produces 4,4-dimethyl-cyclohexanone (355 mg) in a yield of 94% (J. Org. Chem. 2001, 66 (3), 733-738).

後処理

  1. filtrationFiltration over celite
  2. concentrationconcentration
  3. customby evaporation

出典と根拠

ORDレコード
ord-4a9b7976539f4e5b878d784e3b817458
出典データセット
uspto-grants-2010_06
特許番号
US07727979B2

関連ノート

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