Tetrahydrofuran → 4-[(3-Chloro-4-fluorophenyl)amino]-6-[(3-ethoxycarbonyl-1-oxo-2-propen-1-yl)-amino]-7-cyclopropylmethoxy-quinazoline

HRID 120348ノート

反応式

[CH:36]([N:37]([CH:38]([CH3:39])[CH3:40])[CH2:41][CH3:42])([CH3:43])[CH3:44].[Cl:1][C:2](=[O:3])[CH:4]=[CH:5][C:6](=[O:7])[O:8][CH2:9][CH3:10].[NH2:11][c:12]1[cH:13][c:14]2[c:15]([NH:27][c:28]3[cH:29][c:30]([Cl:35])[c:31]([F:34])[cH:32][cH:33]3)[n:16][cH:17][n:18][c:19]2[cH:20][c:21]1[O:22][CH2:23][CH:24]1[CH2:25][CH2:26]1.[O:45]1[CH2:46][CH2:47][CH2:48][CH2:49]1>>[C:2](=[O:3])([CH:4]=[CH:5][C:6](=[O:7])[O:8][CH2:9][CH3:10])[NH:11][c:12]1[cH:13][c:14]2[c:15]([NH:27][c:28]3[cH:29][c:30]([Cl:35])[c:31]([F:34])[cH:32][cH:33]3)[n:16][cH:17][n:18][c:19]2[cH:20][c:21]1[O:22][CH2:23][CH:24]1[CH2:25][CH2:26]1