Tetrahydrofuran → 1-(3-fluoro-5-vinylpyridin-2-yl)-N-(6-fluorobenzo[d]thiazol-2-yl)-1,2,3,6-tetrahydropyridine-4-carboxamide
反応式
[Br:1][c:2]1[cH:3][c:4]([F:27])[c:5]([N:8]2[CH2:9][CH2:10][C:11]([C:14](=[O:15])[NH:16][c:17]3[s:18][c:19]4[c:20]([n:21]3)[cH:22][cH:23][c:24]([F:26])[cH:25]4)=[CH:12][CH2:13]2)[n:6][cH:7]1.[CH2:46]1[O:47][CH2:48][CH2:49][CH2:50]1.[CH3:29][CH2:30][CH2:31][CH2:32][N+:33]([CH2:34][CH2:35][CH2:36][CH3:37])([CH2:38][CH2:39][CH2:40][CH3:41])[CH2:42][CH2:43][CH2:44][CH3:45].[Cl:51][Pd:52][Cl:53].[F-:28]>>[c:2]1([CH:29]=[CH2:30])[cH:3][c:4]([F:27])[c:5]([N:8]2[CH2:9][CH2:10][C:11]([C:14](=[O:15])[NH:16][c:17]3[s:18][c:19]4[c:20]([n:21]3)[cH:22][cH:23][c:24]([F:26])[cH:25]4)=[CH:12][CH2:13]2)[n:6][cH:7]1
