Hydroxyamine hydrochloride → 2-Chloro-6-(4-pyridyl)benzaldoxime
反応式
[Cl:1][C:2]1[CH:9]=[CH:8][CH:7]=[C:6]([C:10]2[CH:15]=[CH:14][N:13]=[CH:12][CH:11]=2)[C:3]=1[CH:4]=O.Cl.[NH2:17][OH:18]>N1C=CC=CC=1>[Cl:1][C:2]1[CH:9]=[CH:8][CH:7]=[C:6]([C:10]2[CH:15]=[CH:14][N:13]=[CH:12][CH:11]=2)[C:3]=1[CH:4]=[N:17][OH:18]参加物
4
実験手順
2-Chloro-6-(4-pyridyl)benzaldehyde (80 mg, 0.37 mmol) was dissolved in pyridine (2 mL) at room temperature. Hydroxylamine hydrochloride (26 mg, 0.38 mmol) was added and the mixture was allowed to stir overnight. The mixture was then concentrated under reduced pressure to obtain 2-chloro-6-(4-pyridyl)benzaldoxime (85 mg, 99% yield). MW=233 confirmed by LC-MS, tr=8.36 min (Method Y) MH+=231–235
後処理
- concentrationThe mixture was then concentrated under reduced pressure
出典と根拠
- ORDレコード
- ord-6826822b0fac4c448f64999aae1ecf01
- 出典データセット
- uspto-grants-2006_10
- 特許番号
- US07115642B2
反応ノート
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