Chlorosulfonic acid → HCID 15480187、化合物

HRID 1250462ノート

反応式

HRID 1250462 の反応式
[O:1]([C:8]1[CH:13]=[CH:12][C:11]([N:14]2[CH:18]=[CH:17][N:16]=[CH:15]2)=[CH:10][CH:9]=1)[C:2]1[CH:7]=[CH:6][CH:5]=[CH:4][CH:3]=1.Cl[S:20]([OH:23])(=[O:22])=[O:21]>C(Cl)(Cl)Cl>[N:14]1([C:11]2[CH:12]=[CH:13][C:8]([O:1][C:2]3[CH:3]=[CH:4][C:5]([S:20]([OH:23])(=[O:22])=[O:21])=[CH:6][CH:7]=3)=[CH:9][CH:10]=2)[CH:18]=[CH:17][N:16]=[CH:15]1

参加物

4

反応物 2

HCID 24638Chlorosulfonic acidHCID 183266381-(4-Phenoxyphenyl)-1H-imidazole

生成物 1

HCID 15480187HCID 15480187、化合物

試薬・触媒・溶媒 1

HCID 6212Chloroform溶媒

実験手順

137 mmol of 1-(4-phenoxyphenyl)imidazole are dissolved in 250 ml of chloroform. 190 mmol of chlorosulphonic acid are then added dropwise. The whole is left at 45° C. overnight. After cooling and removal of the solvent by evaporation, the resulting oil is taken up in diethyl ether. The resulting solid is filtered off and dried to yield the expected product.

後処理

  1. temperatureAfter cooling
  2. customremoval of the solvent
  3. customby evaporation
  4. filtrationThe resulting solid is filtered off
  5. customdried

出典と根拠

ORDレコード
ord-fabf148c68754a6dbcbf2d6965c22220
出典データセット
uspto-grants-2002_01
特許番号
US06339092B1

反応ノート

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