1,1'-Carbonyldiimidazole → 1,3-Dioxo-2-[(1S,2R)-2-phenylcyclopropyl]-N-(4-phenylisoxazol-5-yl)hexahydroimidazo[1,5-a]pyrazine-7(1H)-carboxamide

反応式

[C:1]1([C:7]2[CH:8]=[N:9][O:10][C:11]=2[NH2:12])[CH:6]=[CH:5][CH:4]=[CH:3][CH:2]=1.[Li+].C[Si]([N-][Si](C)(C)C)(C)C.C1N=CN([C:28](N2C=NC=C2)=[O:29])C=1.[C:35]1([C@@H:41]2[CH2:43][C@H:42]2[N:44]2[C:52](=[O:53])[CH:47]3[CH2:48][NH:49][CH2:50][CH2:51][N:46]3[C:45]2=[O:54])[CH:40]=[CH:39][CH:38]=[CH:37][CH:36]=1>C1COCC1>[O:53]=[C:52]1[CH:47]2[CH2:48][N:49]([C:28]([NH:12][C:11]3[O:10][N:9]=[CH:8][C:7]=3[C:1]3[CH:2]=[CH:3][CH:4]=[CH:5][CH:6]=3)=[O:29])[CH2:50][CH2:51][N:46]2[C:45](=[O:54])[N:44]1[C@H:42]1[CH2:43][C@@H:41]1[C:35]1[CH:40]=[CH:39][CH:38]=[CH:37][CH:36]=1