Ethyl vinyl ether → 3-(1-Ethoxyethoxy)but-1-yne

HRID 1262724ノート

反応式

HRID 1262724 の反応式
[CH3:1][CH:2]([OH:5])[C:3]#[CH:4].[CH2:6]([O:8][CH:9]=[CH2:10])[CH3:7].OS([O-])(=O)=O.[K+]>C([O-])([O-])=O.[Na+].[Na+]>[CH3:7][CH:6]([O:5][CH:2]([C:3]#[CH:4])[CH3:1])[O:8][CH2:9][CH3:10]

参加物

5

反応物 3

HCID 8023Ethyl vinyl etherHCID 162393-Butyn-2-olHCID 516920Potassium bisulfate

生成物 1

HCID 100120033-(1-Ethoxyethoxy)but-1-yne収率 91%

試薬・触媒・溶媒 1

HCID 10340Sodium Carbonate触媒

実験手順

A mixture of 200 g of but-3-yn-2-ol and 240 g of ethylvinyl ether was added dropwise, at 30° and under nitrogen atmosphere, to 2 g of previously dried KHSO4. After stirring for 2 hours at 30° the reaction mixture was neutralized with 10 g of Na2CO3, then filtered, the organic phase being finally distilled on a VIGREUX column to give 369 g (91% yield) of 2-(3-oxa-pent-2-yloxy)-but-3-yne having b.p. 31°/16 Torr.

後処理

  1. filtrationfiltered
  2. distillationthe organic phase being finally distilled on a VIGREUX column

出典と根拠

ORDレコード
ord-319c5b058c8d42159c2250cf12f7c2e8
出典データセット
uspto-grants-1984_06
特許番号
US04453013

反応ノート

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