4-Nitroaniline → N-(4-nitrophenyl)-3-chloropropane-1-sulfonamide

HRID 1268817ノート

反応式

HRID 1268817 の反応式
[N+:1]([C:4]1[CH:10]=[CH:9][C:7]([NH2:8])=[CH:6][CH:5]=1)([O-:3])=[O:2].[Cl:11][CH2:12][CH2:13][CH2:14][S:15](Cl)(=[O:17])=[O:16]>N1C=CC=CC=1>[N+:1]([C:4]1[CH:10]=[CH:9][C:7]([NH:8][S:15]([CH2:14][CH2:13][CH2:12][Cl:11])(=[O:17])=[O:16])=[CH:6][CH:5]=1)([O-:3])=[O:2]

参加物

4

反応物 2

HCID 74754-NitroanilineHCID 154103-Chloropropanesulphonyl chloride

生成物 1

HCID 17988807N-(4-nitrophenyl)-3-chloropropane-1-sulfonamide

試薬・触媒・溶媒 1

HCID 1049Pyridine溶媒

実験手順

A solution of 5.00 g (36.2 mmol) of 4-nitroaniline and 6.41 g (36.2 mmol) of 3-chloropropanesulfonyl chloride in 20 ml of pyridine is stirred overnight at room temperature. The reaction mixture is then poured onto ice. The precipitate which deposits in the process is filtered off with suction and dried, giving N-(4-nitrophenyl)-3-chloropropane-1-sulfonamide as a yellowish solid; ESI 279.

後処理

  1. additionThe reaction mixture is then poured onto ice
  2. filtrationis filtered off with suction
  3. customdried

出典と根拠

ORDレコード
ord-dad8a22826ee4ef1ae0115a041e9ed1e
出典データセット
uspto-grants-2007_04
特許番号
US07199133B2

反応ノート

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