Chloride → 2-Methyl-3,4,6-trifluorobenzoyl chloride

反応式

[CH3:1][C:2]1[C:10]([F:11])=[C:9]([F:12])[CH:8]=[C:7]([F:13])[C:3]=1[C:4](O)=[O:5].[Cl-:14]>>[CH3:1][C:2]1[C:10]([F:11])=[C:9]([F:12])[CH:8]=[C:7]([F:13])[C:3]=1[C:4]([Cl:14])=[O:5]

参加物

反応物 2

HCID 312Chloride

HCID 101303052-Methyl-3,4,6-trifluorobenzoic acid

生成物 1

HCID 150076072-Methyl-3,4,6-trifluorobenzoyl chloride

実験手順

To 2-methyl-3,4,6-trifluorobenzoic acid (3.2 g) is added thiony chloride (7 ml) and the mixture is refluxed for 1 hour. After concentrating, 2-methyl-3,4,6-trifluorobenzoyl chloride (3.3 g) is obtained.

後処理

temperaturethe mixture is refluxed for 1 hour
concentrationAfter concentrating

出典と根拠

ORDレコード: ord-141b4f862c4146f6950ca566cd749152
出典データセット: uspto-grants-1998_03
DOI: 10.6084/m9.figshare.5104873.v1
特許番号: US05723648

反応ノート

読み込み中…