(4-Aminophenoxy)benzene → HCID 898756、化合物

HRID 1277817ノート

反応式

HRID 1277817 の反応式
[O:1]([C:8]1[CH:13]=[CH:12][C:11]([NH2:14])=[CH:10][CH:9]=1)[C:2]1[CH:7]=[CH:6][CH:5]=[CH:4][CH:3]=1.Cl[C:16]([O:18][CH2:19][CH3:20])=[O:17]>N1C=CC=CC=1>[O:1]([C:8]1[CH:9]=[CH:10][C:11]([NH:14][C:16](=[O:17])[O:18][CH2:19][CH3:20])=[CH:12][CH:13]=1)[C:2]1[CH:7]=[CH:6][CH:5]=[CH:4][CH:3]=1

参加物

4

反応物 2

HCID 8764(4-Aminophenoxy)benzeneHCID 10928Ethyl chloroformate

生成物 1

HCID 898756HCID 898756、化合物

試薬・触媒・溶媒 1

HCID 1049Pyridine溶媒

反応条件

温度
4 °C

実験手順

4-Phenoxybenzenamine (18.5 grams; 0.1 mole) and pyridine (50 ml) were charged into a glass reaction vessel fitted with a mechanical stirrer and thermometer and cooled to about 4° C. Ethyl chloroformate (13.5 grams; 0.125 mole) was added and the reaction stirred at about 4° C. for a period of about 30 minutes, stirring was then continued at room temperature for another 16 hours. Crystallization occured, whereupon the precipitate was filtered from the reaction medium, washed with water, and air dried to give the desired product ethyl (4-phenoxyphenyl)carbamate.

後処理

  1. customfitted with a mechanical stirrer
  2. stirringstirring
  3. waitwas then continued at room temperature for another 16 hours
  4. customCrystallization
  5. filtrationwas filtered from the reaction medium
  6. washwashed with water, and air
  7. customdried

出典と根拠

ORDレコード
ord-dedada6beb2747c1afa74bb05f7578fb
出典データセット
uspto-grants-1981_07
特許番号
US04279637

反応ノート

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