Ethyl chloroformate → Ethyl [4-(4-methoxyphenoxy)phenyl]carbamate

HRID 1277821

反応式

HRID 1277821 の反応式
[CH3:1][O:2][C:3]1[CH:16]=[CH:15][C:6]([O:7][C:8]2[CH:13]=[CH:12][C:11]([NH2:14])=[CH:10][CH:9]=2)=[CH:5][CH:4]=1.Cl[C:18]([O:20][CH2:21][CH3:22])=[O:19]>N1C=CC=CC=1>[CH3:1][O:2][C:3]1[CH:16]=[CH:15][C:6]([O:7][C:8]2[CH:13]=[CH:12][C:11]([NH:14][C:18](=[O:19])[O:20][CH2:21][CH3:22])=[CH:10][CH:9]=2)=[CH:5][CH:4]=1

参加物

4

反応物 2

HCID 10928Ethyl chloroformateHCID 1014024-(4-Methoxyphenoxy)aniline

生成物 1

HCID 53699951Ethyl [4-(4-methoxyphenoxy)phenyl]carbamate

試薬・触媒・溶媒 1

HCID 1049Pyridine溶媒

反応条件

温度
5 °C

実験手順

4-(4-Methoxyphenoxy)benzenamine (0.1 mole) and pyridine (50 ml) are charged into a glass reaction vessel fitted with a mechanical stirrer and thermometer and are cooled to about 5° C. Ethyl chloroformate (0.125 mole) is added, with stirring, at about 5° C., then for an additional 16 hours at room temperature. The mixture is then washed with 2 portions of water (50 ml), dried and the solvent is then removed to yield the desired product ethyl [4-(4-methoxyphenoxy)phenyl]carbamate.

後処理

  1. customfitted with a mechanical stirrer
  2. washThe mixture is then washed with 2 portions of water (50 ml)
  3. customdried
  4. customthe solvent is then removed

出典と根拠

ORDレコード
ord-baec1ce3f676453eb52cf40e0dd38a70
出典データセット
uspto-grants-1981_07
特許番号
US04279637

関連ノート

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