Naphthalic anhydride → N-Hydroxynaphthalimide

HRID 127984

反応式

HRID 127984 の反応式
C(=O)([O-])[O-].[Na+].[Na+].[CH:7]1[CH:12]=[C:11]2[C:13]([O:15][C:16]([C:18]3=[CH:19][CH:20]=[CH:21][C:9](=[C:10]23)[CH:8]=1)=O)=[O:14].Cl.[NH2:23][OH:24]>>[CH:7]1[CH:12]=[C:11]2[C:13]([N:23]([OH:24])[C:16]([C:18]3=[CH:19][CH:20]=[CH:21][C:9](=[C:10]23)[CH:8]=1)=[O:15])=[O:14]

参加物

4

反応物 3

HCID 6693Naphthalic anhydrideHCID 10340Sodium Carbonate2 回HCID 443297Hydroxyamine hydrochloride

生成物 1

HCID 82263N-Hydroxynaphthalimide

実験手順

To 400 g of an aqueous solution of 3% by weight sodium carbonate were added 24.0 g of 1,8-naphthalic acid anhydride and 10.0 g of hydroxylamine hydrochloride and they were reacted for 2 hours at 90° C. Then, 200 g of an aqueous solution of 10% by weight sodium carbonate was added to the mixture, after filtering away insoluble materials, 100 ml of concentrated hydrochloric acid was added to the mixture, and precipitates formed were collected and recrystallized from ethanol to provide N-hydroxy-1,8-naphthalimide.

後処理

  1. customwere reacted for 2 hours at 90° C
  2. filtrationafter filtering away insoluble materials, 100 ml of concentrated hydrochloric acid
  3. additionwas added to the mixture
  4. customprecipitates
  5. customformed
  6. customwere collected
  7. customrecrystallized from ethanol

出典と根拠

ORDレコード
ord-855ec7073a8a4488a053b4ad8e662956
出典データセット
uspto-grants-1981_03
特許番号
US04258121

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