1,1-Dibromoethane → 2-(2-Bromoethoxy)-1,3-dimethylbenzene
反応式
[OH-].[Na+].[CH3:3][C:4]1[CH:9]=[CH:8][CH:7]=[C:6]([CH3:10])[C:5]=1[OH:11].[Br:12][CH:13](Br)[CH3:14]>O.C(O)C>[CH3:3][C:4]1[CH:9]=[CH:8][CH:7]=[C:6]([CH3:10])[C:5]=1[O:11][CH2:14][CH2:13][Br:12]参加物
6
実験手順
To a solution containing sodium hydroxide (80 g) in water (1 liter) and ethanol (0.5 liter) are added 2,6-dimethyl-phenol (245 g) dissolved in ethanol (0.5 liter), and then dibromoethane (750 g). The mixture is refluxed for 48 hours, under vigorous stirring. It is then extracted with methylene chloride. After washing with dilute aqueous sodium hydroxide and then with water, the solvent is evaporated in vacuo. 2(2,6-Dimethyl-phenoxy)-1-bromo-ethane boils at 148°-150° C./25 mm Hg.
後処理
- temperatureThe mixture is refluxed for 48 hours, under vigorous stirring
- extractionIt is then extracted with methylene chloride
- washAfter washing with dilute aqueous sodium hydroxide
- customwith water, the solvent is evaporated in vacuo
出典と根拠
- ORDレコード
- ord-7b9296f09277488298a19d66a77727f6
- 出典データセット
- uspto-grants-1981_03
- 特許番号
- US04259334
反応ノート
読み込み中…