1,1-Dibromoethane → 2-(2-Bromoethoxy)-1,3-dimethylbenzene

HRID 128204

反応式

HRID 128204 の反応式
[OH-].[Na+].[CH3:3][C:4]1[CH:9]=[CH:8][CH:7]=[C:6]([CH3:10])[C:5]=1[OH:11].[Br:12][CH:13](Br)[CH3:14]>O.C(O)C>[CH3:3][C:4]1[CH:9]=[CH:8][CH:7]=[C:6]([CH3:10])[C:5]=1[O:11][CH2:14][CH2:13][Br:12]

参加物

6

反応物 3

HCID 112011,1-DibromoethaneHCID 113352,6-DimethylphenolHCID 14798Sodium Hydroxide

生成物 1

HCID 24522082-(2-Bromoethoxy)-1,3-dimethylbenzene

試薬・触媒・溶媒 2

HCID 702Ethanol溶媒2 回HCID 962Water溶媒

実験手順

To a solution containing sodium hydroxide (80 g) in water (1 liter) and ethanol (0.5 liter) are added 2,6-dimethyl-phenol (245 g) dissolved in ethanol (0.5 liter), and then dibromoethane (750 g). The mixture is refluxed for 48 hours, under vigorous stirring. It is then extracted with methylene chloride. After washing with dilute aqueous sodium hydroxide and then with water, the solvent is evaporated in vacuo. 2(2,6-Dimethyl-phenoxy)-1-bromo-ethane boils at 148°-150° C./25 mm Hg.

後処理

  1. temperatureThe mixture is refluxed for 48 hours, under vigorous stirring
  2. extractionIt is then extracted with methylene chloride
  3. washAfter washing with dilute aqueous sodium hydroxide
  4. customwith water, the solvent is evaporated in vacuo

出典と根拠

ORDレコード
ord-7b9296f09277488298a19d66a77727f6
出典データセット
uspto-grants-1981_03
特許番号
US04259334

関連ノート

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