Methyl iodide → HCID 21519274、化合物
反応式
[CH3:1][N:2]([CH3:19])[CH2:3][CH:4]([C:6]1([OH:18])[CH2:11][CH2:10][CH2:9][CH2:8][CH:7]1[C:12]1[CH:17]=[CH:16][CH:15]=[CH:14][CH:13]=1)[CH3:5].[CH3:20][I:21]>CCOCC.O1CCCC1>[I-:21].[OH:18][C:6]1([CH:4]([CH3:5])[CH2:3][N+:2]([CH3:20])([CH3:1])[CH3:19])[CH2:11][CH2:10][CH2:9][CH2:8][CH:7]1[C:12]1[CH:13]=[CH:14][CH:15]=[CH:16][CH:17]=1参加物
5
実験手順
A solution of 3.5 grams of 1-(2-dimethylamino-1-methylethyl)-2-phenyl-cyclohexanol in 250 ml ether and 10 ml tetrahydrofuran is treated with 6 ml methyl iodide and allowed to stand for 7 days. The crystalline product is filtered and washed with ether and recrystallized from water giving 2.1 grams melting at 155°-159°C.
後処理
- filtrationThe crystalline product is filtered
- washwashed with ether
- customrecrystallized from water giving 2.1 grams melting at 155°-159°C.
出典と根拠
- ORDレコード
- ord-d523010a4cd2450b9bdfb6ac860fadda
- 出典データセット
- uspto-grants-1976_08
- 特許番号
- US03974157
反応ノート
読み込み中…