反応式
S(Cl)([Cl:3])=O.[NH2:5][CH2:6][CH2:7][CH2:8][CH2:9][CH2:10][CH2:11][CH2:12][C:13]([OH:15])=[O:14].[CH3:16]O>>[ClH:3].[NH2:5][CH2:6][CH2:7][CH2:8][CH2:9][CH2:10][CH2:11][CH2:12][C:13]([O:15][CH3:16])=[O:14]参加物
4
反応条件
- 温度
- 20 °C
実験手順
0.7 cm3 of thionyl chloride is added to a solution of 1 g of 8-aminooctanoic acid in 40 cm3 of methanol at a temperature in the region of -20° C. and stirring is maintained for 12 hours at a temperature in the region of 20° C. The solvent is removed under reduced pressure (2.7 kPa) at a temperature in the region of 35° C. 1.48 g of methyl 8-aminooctanoate hydrochloride is thus obtained in the form of a white solid.
後処理
- customThe solvent is removed under reduced pressure (2.7 kPa) at a temperature in the region of 35° C
出典と根拠
- ORDレコード
- ord-678f33cd827b41fe9bb0c6f946066656
- 出典データセット
- uspto-grants-1995_11
- 特許番号
- US05468888
関連ノート
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