3-Pyridinecarboxaldehyde → HCID 22857565、化合物

HRID 129753

反応式

HRID 129753 の反応式
[N:1]1[CH:6]=[CH:5][CH:4]=[C:3]([CH:7]=O)[CH:2]=1.[NH2:9][C@@H:10]([C:13]([OH:15])=[O:14])[CH2:11][SH:12]>C(O)C>[N:1]1[CH:6]=[CH:5][CH:4]=[C:3]([CH:7]2[NH:9][C@@H:10]([C:13]([OH:15])=[O:14])[CH2:11][S:12]2)[CH:2]=1

参加物

4

反応物 2

HCID 103713-PyridinecarboxaldehydeHCID 92851D-Cysteine

生成物 1

HCID 22857565HCID 22857565、化合物収率 54%

試薬・触媒・溶媒 1

HCID 702Ethanol溶媒

実験手順

A solution of 1.07 g of pyridine-3-aldehyde and 1.21 g of D-cysteine in 60% v/v aqueous ethanol was heated under reflux for 4 hours. The mixture was cooled to room temperature and the resulting solid material was removed by filtration. The filtrate was concentrated by evaporation under reduced pressure, and 5 ml of ethanol were added to the resulting residue. Collecting the precipitated crystals by filtration gave 1.13 g (yield 54%) of the title compound, melting at 138°-139° C.

後処理

  1. temperatureunder reflux for 4 hours
  2. customthe resulting solid material was removed by filtration
  3. concentrationThe filtrate was concentrated by evaporation under reduced pressure, and 5 ml of ethanol
  4. additionwere added to the resulting residue
  5. customCollecting the precipitated crystals
  6. filtrationby filtration

出典と根拠

ORDレコード
ord-492bc5de6e494e6abeed9560618fc5f6
出典データセット
uspto-grants-1995_11
特許番号
US05470851

関連ノート

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