Sodium borohydride → N-[(6R,7S)-2-fluoro-9-(2-hydroxy-ethyl)-6-methyl-8-oxo-6,7,8,9-tetrahydro-5-oxa-9-aza-benzocyclohepten-7-yl]-2-hydroxy-2-methyl-N-(2,2,3,3,3-pentafluoro-propyl)-malonamide

反応式

[F:1][C:2]1[CH:3]=[CH:4][C:5]2[O:11][C@H:10]([CH3:12])[C@H:9]([N:13]([CH2:22][C:23]([F:29])([F:28])[C:24]([F:27])([F:26])[F:25])[C:14](=[O:21])[C:15]([OH:20])([CH3:19])[C:16]([NH2:18])=[O:17])[C:8](=[O:30])[N:7]([CH2:31][CH:32]=[O:33])[C:6]=2[CH:34]=1.[BH4-].[Na+].C(OC(=O)C)C.CCCCCCC>O1CCCC1>[F:1][C:2]1[CH:3]=[CH:4][C:5]2[O:11][C@H:10]([CH3:12])[C@H:9]([N:13]([CH2:22][C:23]([F:28])([F:29])[C:24]([F:25])([F:26])[F:27])[C:14](=[O:21])[C:15]([OH:20])([CH3:19])[C:16]([NH2:18])=[O:17])[C:8](=[O:30])[N:7]([CH2:31][CH2:32][OH:33])[C:6]=2[CH:34]=1