Sodium hydride → HCID 58640416、化合物
反応式
[CH3:1][C:2]1([CH3:13])[CH2:11][CH2:10][CH2:9][C:8]2[CH:7]=[C:6]([OH:12])[CH:5]=[CH:4][C:3]1=2.[H-].[Na+].Br[CH2:17][C:18]([O:20][C:21]([CH3:24])([CH3:23])[CH3:22])=[O:19]>O1CCCC1>[CH3:1][C:2]1([CH3:13])[CH2:11][CH2:10][CH2:9][C:8]2[CH:7]=[C:6]([O:12][CH2:17][C:18]([O:20][C:21]([CH3:24])([CH3:23])[CH3:22])=[O:19])[CH:5]=[CH:4][C:3]1=2参加物
5
実験手順
A mixture of 5,5-dimethyl-5,6,7,8-tetrahydronaphthalen-2-ol (2.0 g, 11.3 mmol), 60% sodium hydride (542 mg, 13.2 mmol), tert-butyl bromoacetate (3.3 g, 17 mmol) and tetrahydrofuran (THF) (10 ml) was treated in the same procedure described in Example 3(a) to furnish 2.8 g of the title compound as a white solid.
後処理
- additionwas treated in the same procedure
出典と根拠
- ORDレコード
- ord-e45a36b684a04e32a319486166f23bda
- 出典データセット
- uspto-grants-2007_05
- 特許番号
- US07214824B2
反応ノート
読み込み中…