N-bromobutanimide → 3-(Bromomethyl)phenyl acetate

HRID 1351087ノート

反応式

HRID 1351087 の反応式
[C:1]([O:4][C:5]1[CH:6]=[C:7]([CH3:11])[CH:8]=[CH:9][CH:10]=1)(=[O:3])[CH3:2].[Br:12]N1C(=O)CCC1=O>ClC(Cl)(Cl)Cl.N(C(C)(C)C#N)=NC(C)(C)C#N>[C:1]([O:4][C:5]1[CH:10]=[CH:9][CH:8]=[C:7]([CH2:11][Br:12])[CH:6]=1)(=[O:3])[CH3:2]

参加物

5

反応物 2

HCID 67184N-bromobutanimideHCID 67406Cresatin

生成物 1

HCID 64220753-(Bromomethyl)phenyl acetate収率 100.4%

試薬・触媒・溶媒 2

HCID 6547Azobisisobutyronitrile触媒HCID 5943Carbon Tetrachloride溶媒

実験手順

A suspension of m-tolyl acetate (583 mg), N-bromosuccinimide (691 mg) and α,α′-azobis(isobutyronitrile) (13 mg) in tetrachloromethane (10 mL) was refluxed for 1 hour. The reaction mixture was cooled to room temperature, and the insoluble material was removed by filtration. The filtrate was concentrated to give the title compound (893 mg).

後処理

  1. temperaturewas refluxed for 1 hour
  2. customthe insoluble material was removed by filtration
  3. concentrationThe filtrate was concentrated

出典と根拠

ORDレコード
ord-d803bf4dc0984eeba3872c4297924e16
出典データセット
uspto-grants-2007_05
特許番号
US07217697B2

反応ノート

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