Hydrochloric Acid → 2,4'-Dichloroacetanilide

HRID 1354343

反応式

HRID 1354343 の反応式
[Cl:1][CH2:2][C:3](Cl)=[O:4].[Cl:6][C:7]1[CH:13]=[CH:12][C:10]([NH2:11])=[CH:9][CH:8]=1.Cl>O1CCOCC1>[Cl:6][C:7]1[CH:13]=[CH:12][C:10]([NH:11][C:3](=[O:4])[CH2:2][Cl:1])=[CH:9][CH:8]=1

参加物

5

反応物 3

HCID 313Hydrochloric AcidHCID 6577Chloroacetyl chlorideHCID 78124-Chloroaniline

生成物 1

HCID 949202,4'-Dichloroacetanilide

試薬・触媒・溶媒 1

HCID 312751,4-Dioxane溶媒

実験手順

3.4 g (30 mol) of 2-chloroacetyl chloride were dissolved in anhydrous dioxane and a solution containing 3.8 g (30 mol) of 4-chloroaniline was added dropwise. After an hour, the batch was poured into ice water, acidified using dilute hydrochloric acid, the supernatant was removed by suction and the residue was washed with water until neutral. The reaction product was recrystallized from ethanol. The yield was 3.2 g.

後処理

  1. additionwas added dropwise
  2. waitAfter an hour
  3. customthe supernatant was removed by suction
  4. washthe residue was washed with water until neutral
  5. customThe reaction product was recrystallized from ethanol

出典と根拠

ORDレコード
ord-adf3d798277641cc8b923af5e83e894e
出典データセット
uspto-grants-2007_05
特許番号
US07223781B2

関連ノート

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