Dimethylformamide → 4-Formylbenzoyl chloride

HRID 13549

反応式

HRID 13549 の反応式
[C:1]([C:4]1[CH:11]=[CH:10][C:7]([CH:8]=[O:9])=[CH:6][CH:5]=1)(O)=[O:2].S(Cl)([Cl:14])=O.CN(C=O)C>C1(C)C=CC=CC=1>[CH:8]([C:7]1[CH:10]=[CH:11][C:4]([C:1]([Cl:14])=[O:2])=[CH:5][CH:6]=1)=[O:9]

参加物

5

反応物 3

HCID 6228DimethylformamideHCID 120884-Formylbenzoic acidHCID 24386Thionyl Chloride

生成物 1

HCID 124246204-Formylbenzoyl chloride

試薬・触媒・溶媒 1

HCID 1140Toluene溶媒2 回

反応条件

温度
100 °C

実験手順

A solution of 4-carboxybenzaldehyde (30.0 g, 0.200 mol) in toluene (300 mL) was treated with thionyl chloride (28.6 g, 0.240 mol) and DMF (1.0 mL). The reaction mixture was heated at 100° C. for 2 h, during which time the solids dissolved to yield a pale yellow colored solution. The reaction mixture was cooled to 0° C. to yield a solution of the title compound in toluene, which was used without further manipulation.

後処理

  1. dissolutiondissolved
  2. customto yield a pale yellow colored solution
  3. temperatureThe reaction mixture was cooled to 0° C.

出典と根拠

ORDレコード
ord-abc6f75142d542af8371fa9c0841d003
出典データセット
uspto-grants-2010_06
特許番号
US07728129B2

関連ノート

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